I drive a 2010 Toyota Sequoia that we got for towing our 26′ travel trailer. Not long after I got my ham license I decided that the thing to do was to put a mobile radio in it. I did a fair amount of research beforehand, and what follows is what I ended up doing.
I’ll start where most things start, under the hood at the battery:
I got a spool of 10-gauge wire and began at the battery with screw-on connectors that lead to a pair of 50A fuses. I’d call them the fuses of last resort, since there’s more fusing downstream, so hopefully these will never blow. The wire goes first to an Anderson Power Pole connector for quick disconnect of everthing, should that ever be needed.
Oh well.